University of Manchester Breast Centre

Researchers at the University of Manchester use advanced in vitro and in vivo preclinical models to investigate early and metastatic human breast cancer leading to the development of new strategies or targets for prevention of advanced breast cancer.

We have produced an experimental resource of 12 PDXs from primary and metastatic breast tumours that we have shown to maintain histopathological features and genetic profiles of the original patient tumours.

Manchester Breast Centre, University of Manchester is a member of the EurOPDX Consortium. EurOPDX is supported by the European Union's Horizon 2020 research and innovation programme under the grant agreement No. 731105 EDIReX.